Altun, H., Sahin, N., Belge Kurutas, E., & Güngör, O. (2018). Homocysteine, Pyridoxine, Folate and Vitamin B12 Levels in Children with Attention Deficit Hyperactivity Disorder. Psychiatria Danubina, 30(3), 310–316. https://doi.org/10.24869/psyd.2018.310
Baumeister, F. A., Gsell, W., Shin, Y. S., & Egger, J. (1994). Glutamate in pyridoxine-dependent epilepsy: Neurotoxic glutamate concentration in the cerebrospinal fluid and its normalization by pyridoxine. Pediatrics, 94(3), 318–321.
Bender, D. A. (1999). Non-nutritional uses of vitamin B6. The British Journal of Nutrition, 81(1), 7–20.
Bilski, P., Li, M. Y., Ehrenshaft, M., Daub, M. E., & Chignell, C. F. (2000). Vitamin B6 (pyridoxine) and its derivatives are efficient singlet oxygen quenchers and potential fungal antioxidants. Photochemistry and Photobiology, 71(2), 129–134. https://doi.org/10.1562/0031-8655(2000)071<0129:sipvbp>2.0.co;2
Blom, H. J., & Smulders, Y. (2011). Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects. Journal of Inherited Metabolic Disease, 34(1), 75–81. https://doi.org/10.1007/s10545-010-9177-4
Brown, M. J., Ameer, M. A., & Beier, K. (2020). Vitamin B6 Deficiency (Pyridoxine). In StatPearls. StatPearls Publishing. http://www.ncbi.nlm.nih.gov/books/NBK470579/
Calderón-Ospina, C. A., & Nava-Mesa, M. O. (2020). B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin. CNS Neuroscience & Therapeutics, 26(1), 5–13. https://doi.org/10.1111/cns.13207
Carter, T. C., Pangilinan, F., Molloy, A. M., Fan, R., Wang, Y., Shane, B., Gibney, E. R., Midttun, Ø., Ueland, P. M., Cropp, C. D., Kim, Y., Wilson, A. F., Bailey-Wilson, J. E., Brody, L. C., & Mills, J. L. (2015). Common Variants at Putative Regulatory Sites of the Tissue Nonspecific Alkaline Phosphatase Gene Influence Circulating Pyridoxal 5’-Phosphate Concentration in Healthy Adults. The Journal of Nutrition, 145(7), 1386–1393. https://doi.org/10.3945/jn.114.208769
Cook, C. C., Hallwood, P. M., & Thomson, A. D. (1998). B Vitamin deficiency and neuropsychiatric syndromes in alcohol misuse. Alcohol and Alcoholism (Oxford, Oxfordshire), 33(4), 317–336. https://doi.org/10.1093/oxfordjournals.alcalc.a008400
Dalto, D. B., & Matte, J.-J. (2017). Pyridoxine (Vitamin B6) and the Glutathione Peroxidase System; a Link between One-Carbon Metabolism and Antioxidation. Nutrients, 9(3). https://doi.org/10.3390/nu9030189
de Lau, L. M. L., Koudstaal, P. J., Witteman, J. C. M., Hofman, A., & Breteler, M. M. B. (2006). Dietary folate, vitamin B12, and vitamin B6 and the risk of Parkinson disease. Neurology, 67(2), 315–318. https://doi.org/10.1212/01.wnl.0000225050.57553.6d
Ebrahimi, E., Khayati Motlagh, S., Nemati, S., & Tavakoli, Z. (2012). Effects of Magnesium and Vitamin B6 on the Severity of Premenstrual Syndrome Symptoms. Journal of Caring Sciences, 1(4), 183–189. https://doi.org/10.5681/jcs.2012.026
Farmacotherapeutisch Kompas, z.d. Pyridoxine. Geraadgpleegd op 11 september 2020: https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/p/pyridoxine#interacties
Fishman, S. M., Christian, P., & West, K. P. (2000). The role of vitamins in the prevention and control of anaemia. Public Health Nutrition, 3(2), 125–150. https://doi.org/10.1017/s1368980000000173
Gougeon, L., Payette, H., Morais, J. A., Gaudreau, P., Shatenstein, B., & Gray-Donald, K. (2016). Intakes of folate, vitamin B6 and B12 and risk of depression in community-dwelling older adults: The Quebec Longitudinal Study on Nutrition and Aging. European Journal of Clinical Nutrition, 70(3), 380–385. https://doi.org/10.1038/ejcn.2015.202
Hemminger, A., & Wills, B. K. (2020). Vitamin B6 Toxicity. In StatPearls. StatPearls Publishing. http://www.ncbi.nlm.nih.gov/books/NBK554500/
Hoyer-Kuhn, H., Kohbrok, S., Volland, R., Franklin, J., Hero, B., Beck, B. B., & Hoppe, B. (2014). Vitamin B6 in primary hyperoxaluria I: First prospective trial after 40 years of practice. Clinical Journal of the American Society of Nephrology: CJASN, 9(3), 468–477. https://doi.org/10.2215/CJN.06820613
Hvas, A.-M., Juul, S., Bech, P., & Nexø, E. (2004). Vitamin B6 level is associated with symptoms of depression. Psychotherapy and Psychosomatics, 73(6), 340–343. https://doi.org/10.1159/000080386
Hughes, C. F., Ward, M., Tracey, F., Hoey, L., Molloy, A. M., Pentieva, K., & McNulty, H. (2017). B-Vitamin Intake and Biomarker Status in Relation to Cognitive Decline in Healthy Older Adults in a 4-Year Follow-Up Study. Nutrients, 9(1). https://doi.org/10.3390/nu9010053
Kashanian, M., Mazinani, R., Jalalmanesh, S., & Babayanzad Ahari, S. (2007). Pyridoxine (vitamin B6) therapy for premenstrual syndrome. International Journal of Gynaecology and Obstetrics: The Official Organ of the International Federation of Gynaecology and Obstetrics, 96(1), 43–44. https://doi.org/10.1016/j.ijgo.2006.09.014
Kennedy, D. O. (2016). B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review. Nutrients, 8(2), 68. https://doi.org/10.3390/nu8020068
Kjeldby, I. K., Fosnes, G. S., Ligaarden, S. C., & Farup, P. G. (2013). Vitamin B6 deficiency and diseases in elderly people—A study in nursing homes. BMC geriatrics, 13, 13. https://doi.org/10.1186/1471-2318-13-13
Lerner, V., Miodownik, C., Kaptsan, A., Cohen, H., Matar, M., Loewenthal, U., & Kotler, M. (2001). Vitamin B(6) in the treatment of tardive dyskinesia: A double-blind, placebo-controlled, crossover study. The American Journal of Psychiatry, 158(9), 1511–1514. https://doi.org/10.1176/appi.ajp.158.9.1511
Lerner, V., Miodownik, C., Kaptsan, A., Cohen, H., Loewenthal, U., & Kotler, M. (2002). Vitamin B6 as add-on treatment in chronic schizophrenic and schizoaffective patients: A double-blind, placebo-controlled study. The Journal of Clinical Psychiatry, 63(1), 54–58. https://doi.org/10.4088/jcp.v63n0111
Lerner, V., Miodownik, C., Kaptsan, A., Bersudsky, Y., Libov, I., Sela, B.-A., & Witztum, E. (2007). Vitamin B6 treatment for tardive dyskinesia: A randomized, double-blind, placebo-controlled, crossover study. The Journal of Clinical Psychiatry, 68(11), 1648–1654. https://doi.org/10.4088/jcp.v68n1103
Ligaarden, S. C., & Farup, P. G. (2011). Low intake of vitamin B6 is associated with irritable bowel syndrome symptoms. Nutrition Research (New York, N.Y.), 31(5), 356–361. https://doi.org/10.1016/j.nutres.2011.04.001
MacKenzie, K. E., Wiltshire, E. J., Gent, R., Hirte, C., Piotto, L., & Couper, J. J. (2006). Folate and vitamin B6 rapidly normalize endothelial dysfunction in children with type 1 diabetes mellitus. Pediatrics, 118(1), 242–253. https://doi.org/10.1542/peds.2005-2143
Maron, B. A., & Loscalzo, J. (2009). The Treatment of Hyperhomocysteinemia. Annual Review of Medicine, 60(1), 39–54. https://doi.org/10.1146/annurev.med.60.041807.123308
Mascolo, E., & Vernì, F. (2020). Vitamin B6 and Diabetes: Relationship and Molecular Mechanisms. International Journal of Molecular Sciences, 21(10), 3669. https://doi.org/10.3390/ijms21103669
Mason, D. Y., & Emerson, P. M. (1973). Primary acquired sideroblastic anaemia: Response to treatment with pyridoxal-5-phosphate. British Medical Journal, 1(5850), 389–390. https://doi.org/10.1136/bmj.1.5850.389
McParlin, C., O’Donnell, A., Robson, S. C., Beyer, F., Moloney, E., Bryant, A., Bradley, J., Muirhead, C. R., Nelson-Piercy, C., Newbury-Birch, D., Norman, J., Shaw, C., Simpson, E., Swallow, B., Yates, L., & Vale, L. (2016). Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review. JAMA, 316(13), 1392–1401. https://doi.org/10.1001/jama.2016.14337
Meydani, S. N., Ribaya-Mercado, J. D., Russell, R. M., Sahyoun, N., Morrow, F. D., & Gershoff, S. N. (1991). Vitamin B-6 deficiency impairs interleukin 2 production and lymphocyte proliferation in elderly adults. The American Journal of Clinical Nutrition, 53(5), 1275–1280. https://doi.org/10.1093/ajcn/53.5.1275
Ministerie van Volksgezondheid, Welzijn en Sport. (2018). Regeling van de Minister voor Medische Zorg van 20 augustus 2018, 1364645-177989-VGP, houdende het verlenen van vrijstelling voor de aanwezigheid van bepaalde vitamines in voedingssupplementen (Warenwetregeling vrijstelling voedingssupplementen). Geraadpleegd op: https://zoek.officielebekendmakingen.nl/stcrt-2018-47982.pdf
Mikkelsen, K., & Apostolopoulos, V. (2018). B Vitamins and Ageing. In J. R. Harris & V. I. Korolchuk (Red.), Biochemistry and Cell Biology of Ageing: Part I Biomedical Science (Vol. 90, pp. 451–470). Springer Singapore. https://doi.org/10.1007/978-981-13-2835-0_15
Morris, M. S., Picciano, M. F., Jacques, P. F., & Selhub, J. (2008). Plasma pyridoxal 5’-phosphate in the US population: The National Health and Nutrition Examination Survey, 2003-2004. The American Journal of Clinical Nutrition, 87(5), 1446–1454. https://doi.org/10.1093/ajcn/87.5.1446
Muskiet, F. A. J. (2016). Vitamine B6, een oninteressante vitamine, of toch niet? Voedingsgeneeskunde, 17(6), 44–45.
Nakamura, S., Li, H., Adijiang, A., Pischetsrieder, M., & Niwa, T. (2007). Pyridoxal phosphate prevents progression of diabetic nephropathy. Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant Association - European Renal Association, 22(8), 2165–2174. https://doi.org/10.1093/ndt/gfm166
Natural Medicines. Vitamin B6/Professional handout/Interactions. https://naturalmedicines.therapeuticresearch.com. Geraadpleegd op: 11 september 2020
Nederlandse Voedsel- en Warenautoriteit (NVWA). Advies van BuRO over vitamine B6 uit voedingssupplementen. Geraadpleegd op 21 september 2020: https://www.nvwa.nl/documenten/consument/eten-drinken-roken/supplementen-en-preparaten/risicobeoordelingen/advies-van-buro-over-vitamine-b6-uit-voedingssupplementen
Obara, T., Ishikuro, M., Tamiya, G., Ueki, M., Yamanaka, C., Mizuno, S., Kikuya, M., Metoki, H., Matsubara, H., Nagai, M., Kobayashi, T., Kamiyama, M., Watanabe, M., Kakuta, K., Ouchi, M., Kurihara, A., Fukuchi, N., Yasuhara, A., Inagaki, M., … Kuriyama, S. (2018). Potential identification of vitamin B6 responsiveness in autism spectrum disorder utilizing phenotype variables and machine learning methods. Scientific Reports, 8. https://doi.org/10.1038/s41598-018-33110-w
Parra, M., Stahl, S., & Hellmann, H. (2018). Vitamin B6 and Its Role in Cell Metabolism and Physiology. Cells, 7(7). https://doi.org/10.3390/cells7070084
Persaud, N., Meaney, C., El-Emam, K., Moineddin, R., & Thorpe, K. (2018). Doxylamine-pyridoxine for nausea and vomiting of pregnancy randomized placebo controlled trial: Prespecified analyses and reanalysis. PLoS ONE, 13(1). https://doi.org/10.1371/journal.pone.0189978
Pusceddu, I., Herrmann, W., Kleber, M. E., Scharnagl, H., Hoffmann, M. M., Winklhofer-Roob, B. M., März, W., & Herrmann, M. (2020). Subclinical inflammation, telomere shortening, homocysteine, vitamin B6, and mortality: The Ludwigshafen Risk and Cardiovascular Health Study. European Journal of Nutrition, 59(4), 1399–1411. https://doi.org/10.1007/s00394-019-01993-8
Qin, B., Xun, P., Jacobs, D. R., Zhu, N., Daviglus, M. L., Reis, J. P., Steffen, L. M., Van Horn, L., Sidney, S., & He, K. (2017). Intake of niacin, folate, vitamin B-6, and vitamin B-12 through young adulthood and cognitive function in midlife: The Coronary Artery Risk Development in Young Adults (CARDIA) study. The American Journal of Clinical Nutrition, 106(4), 1032–1040. https://doi.org/10.3945/ajcn.117.157834
Ramos, R. J., Albersen, M., Vringer, E., Bosma, M., Zwakenberg, S., Zwartkruis, F., Jans, J. J. M., & Verhoeven-Duif, N. M. (2019). Discovery of pyridoxal reductase activity as part of human vitamin B6 metabolism. Biochimica Et Biophysica Acta. General Subjects, 1863(6), 1088–1097. https://doi.org/10.1016/j.bbagen.2019.03.019
Rijksinstituut voor Volksgezondheid en Milieu (RIVM). Voedselconsumptiepeiling 2012-2016. Gepubliceerd op 20 november 2019 op www.wateetnederland.nl.
Rimm, E. B., Willett, W. C., Hu, F. B., Sampson, L., Colditz, G. A., Manson, J. E., Hennekens, C., & Stampfer, M. J. (1998). Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women. JAMA, 279(5), 359–364. https://doi.org/10.1001/jama.279.5.359
Sacharow, S. J., Picker, J. D., & Levy, H. L. (1993). Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency. In M. P. Adam, H. H. Ardinger, R. A. Pagon, S. E. Wallace, L. J. Bean, K. Stephens, & A. Amemiya (Red.), GeneReviews®. University of Washington, Seattle. http://www.ncbi.nlm.nih.gov/books/NBK1524/
Sakakeeny, L., Roubenoff, R., Obin, M., Fontes, J. D., Benjamin, E. J., Bujanover, Y., Jacques, P. F., & Selhub, J. (2012). Plasma pyridoxal-5-phosphate is inversely associated with systemic markers of inflammation in a population of U.S. adults. The Journal of Nutrition, 142(7), 1280–1285. https://doi.org/10.3945/jn.111.153056
Sato, K. (2018). Why is vitamin B6 effective in alleviating the symptoms of autism? Medical Hypotheses, 115, 103–106. https://doi.org/10.1016/j.mehy.2018.04.007
Schuitemaker, G. E. (2016). Hoge dosis vitamine B6—Neuropathie door hoge B6 …. Of lage B12. Ortho, 34(2), 60–62.
Schuitemaker, G. E. (2019). Hoe zit het nu eigenlijk met vitamine B6—Acht vragen over de maximalisering van de dagdosis. Fit met Voeding, 27(1), 18–20.
Selhub, J., Byun, A., Liu, Z., Mason, J. B., Bronson, R. T., & Crott, J. W. (2013). Dietary vitamin B6 intake modulates colonic inflammation in the IL10-/- model of inflammatory bowel disease. The Journal of Nutritional Biochemistry, 24(12), 2138–2143. https://doi.org/10.1016/j.jnutbio.2013.08.005
Shevchuk, S. V., Postovitenko, K. P., Iliuk, I. A., Bezsmertna, H. V., Bezsmertnyi, Y. O., Kurylenko, I. V., Biloshytska, A. V., & Baranova, I. V. (2019). The relationship between homocysteine level and vitamins B12, B9 and B6 status in patients with chronic kidney disease. Wiadomosci Lekarskie (Warsaw, Poland: 1960), 72(4), 532–538.
Skarupski, K. A., Tangney, C., Li, H., Ouyang, B., Evans, D. A., & Morris, M. C. (2010). Longitudinal association of vitamin B-6, folate, and vitamin B-12 with depressive symptoms among older adults over time. The American Journal of Clinical Nutrition, 92(2), 330–335. https://doi.org/10.3945/ajcn.2010.29413
Smith, A. D. (2008). The worldwide challenge of the dementias: A role for B vitamins and homocysteine? Food and Nutrition Bulletin, 29(2 Suppl), S143-172. https://doi.org/10.1177/15648265080292S119
Sohrabvand, F., Shariat, M., & Haghollahi, F. (2006). Vitamin B supplementation for leg cramps during pregnancy. International Journal of Gynaecology and Obstetrics: The Official Organ of the International Federation of Gynaecology and Obstetrics, 95(1), 48–49. https://doi.org/10.1016/j.ijgo.2006.05.034
Spinneker, A., Sola, R., Lemmen, V., Castillo, M. J., Pietrzik, K., & González-Gross, M. (2007). Vitamin B6 status, deficiency and its consequences—An overview. Nutricion Hospitalaria, 22(1), 7–24.
Stockler, S., Plecko, B., Gospe, S. M., Coulter-Mackie, M., Connolly, M., van Karnebeek, C., Mercimek-Mahmutoglu, S., Hartmann, H., Scharer, G., Struijs, E., Tein, I., Jakobs, C., Clayton, P., & Van Hove, J. L. K. (2011). Pyridoxine dependent epilepsy and antiquitin deficiency: Clinical and molecular characteristics and recommendations for diagnosis, treatment and follow-up. Molecular Genetics and Metabolism, 104(1–2), 48–60. https://doi.org/10.1016/j.ymgme.2011.05.014
Talebi, M., Andalib, S., Bakhti, S., Ayromlou, H., Aghili, A., & Talebi, A. (2013). Effect of Vitamin B6 on Clinical Symptoms and Electrodiagnostic Results of Patients with Carpal Tunnel Syndrome [Text/html]. Advanced Pharmaceutical Bulletin; EISSN 2251-7308. https://doi.org/10.5681/APB.2013.046
Thompson, B., & Amoroso, L. (2014). Improving diets and nutrition: Food-based approaches. CABI?; Food and Agriculture Organization of the United Nations. https://www.researchgate.net/publication/275963287_Improving_Diets_and_Nutrition_-_Food-Based_Approaches
Ueland, P. M., McCann, A., Midttun, Ø., & Ulvik, A. (2017). Inflammation, vitamin B6 and related pathways. Molecular Aspects of Medicine, 53, 10–27. https://doi.org/10.1016/j.mam.2016.08.001
Umar, M. U., Isa, A. A., & Abba, A. H. (2016). High dose pyridoxine for the treatment of tardive dyskinesia: Clinical case and review of literature. Therapeutic Advances in Psychopharmacology, 6(2), 152–156. https://doi.org/10.1177/2045125315616738
van der Griend, R., Biesma, D. H., Haas, F. J., Faber, J. A., Duran, M., Meuwissen, O. J., & Banga, J. D. (2000). The effect of different treatment regimens in reducing fasting and postmethionine-load homocysteine concentrations. Journal of Internal Medicine, 248(3), 223–229. https://doi.org/10.1046/j.1365-2796.2000.00726.x
van Hunsel, F., van de Koppel, S., van Puijenbroek, E., & Kant, A. (2018). Vitamin B6 in Health Supplements and Neuropathy: Case Series Assessment of Spontaneously Reported Cases. Drug Safety, 41(9), 859–869. https://doi.org/10.1007/s40264-018-0664-0
van Stigt, Y. (2019). Hoe zit het echt met vitamine B6? Is vitamine B6 veilig of niet?
Vanuzzo, D., Pilotto, L., Lombardi, R., Lazzerini, G., Carluccio, M., Diviacco, S., Quadrifoglio, F., Danek, G., Gregori, D., Fioretti, P., Cattaneo, M., & De Caterina, R. (2007). Both vitamin B6 and total homocysteine plasma levels predict long-term atherothrombotic events in healthy subjects. European Heart Journal, 28(4), 484–491. https://doi.org/10.1093/eurheartj/ehl470
Vrolijk, M. F., Opperhuizen, A., Jansen, E. H. J. M., Hageman, G. J., Bast, A., & Haenen, G. R. M. M. (2017). The vitamin B6 paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6 function. Toxicology in Vitro, 44, 206–212. https://doi.org/10.1016/j.tiv.2017.07.009
Vitamin B6. Linus Pauling Institute, Micronutrient Information Center, Oregon State University, 2018.
Voedingscentrum. https://www.voedingscentrum.nl/encyclopedie/vitamine-b6.aspx \
Walker, M. J., Morris, L. M., & Cheng, D. (2010). Improvement of cutaneous sensitivity in diabetic peripheral neuropathy with combination L-methylfolate, methylcobalamin, and pyridoxal 5’-phosphate. Reviews in Neurological Diseases, 7(4), 132–139.
Wei, Y., Lu, M., Mei, M., Wang, H., Han, Z., Chen, M., Yao, H., Song, N., Ding, X., Ding, J., Xiao, M., & Hu, G. (2020). Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection. Nature Communications, 11(1), 941. https://doi.org/10.1038/s41467-020-14788-x
Whelan, A. M., Jurgens, T. M., & Naylor, H. (2009). Herbs, vitamins and minerals in the treatment of premenstrual syndrome: a systematic review. Journal of Population Therapeutics and Clinical Pharmacology, 16(3), Article 3. https://www.jptcp.com/index.php/jptcp/article/view/542
Wyatt, K. M., Dimmock, P. W., Jones, P. W., & Shaughn O’Brien, P. M. (1999). Efficacy of vitamin B-6 in the treatment of premenstrual syndrome: Systematic review. BMJ (Clinical Research Ed.), 318(7195), 1375–1381. https://doi.org/10.1136/bmj.318.7195.1375
Wilson, M. P., Plecko, B., Mills, P. B., & Clayton, P. T. (2019). Disorders affecting vitamin B6 metabolism. Journal of Inherited Metabolic Disease, 42(4), 629–646. https://doi.org/10.1002/jimd.12060
